2008

Impact

1.    

Mahtab EAF, Wijffels MCEF, van den Akker NMS, Hahurij ND, Lie Venema H, Wisse LJ, DeRuiter MC, Uhrin P, Zaujec J, Binder BR, Schalij MJ, Poelmann RE, Gittenberger DeGroot AC.   Cardiac malformations and myocardial abnormalities in Podoplanin knockout mouse embryos: Correlation with abnormal epicardial development.   Development Dynamics 2008, Vol. 237, p847-857.

3.169

2.    

Luydendyk JP, Schabbauer GA, Tencati M, Holscher RP, Mackmann N.   Genetic analysis of the role of the P13K-Akt Pathway in Lipopolysaccharide-induced cytokine and tissue factor gene expression in Monocytes/Macrophages .   J of Immunol 2008, Vol. 180, p4218-4226.

6.239

3.    

Pfistershammer K, Klauser C, Leitner J, Stoeckl J, Majdic O, Weichhart T, Sobanov Y, Bochkov V, Saemann M, Zlabinger G, Steinberger P.   Identification of the scavenger receptors SREC-I, Cla-1 (SR-BI), and SR-AI as cellular receptors for Tamm-Horsfall protein.   J Leukoc Biol 2008, Vol. 83, p131-138.

4.572

4.    

Seyerl M, Blueml S, Kirchberger S, Bochkov VN, Oskolkova O, Majdic O, Stoeckl J.   Oxidized phospholipids induce anergy in human peripheral blood T cells.   Eur J Immunol 2008, Vol. 38 p778-787.

4.772

5.    

Kastl SP, Speidl WS, Kaun C, Katsaros KM, Rega G, Afonyushkin T, Bochkov VN, Valent P, Assadian A, Hagmueller GW, Hoeth M, de Martin R, Ma Y, Maurer G, Huber K, Wojta J.   In human macrophages the complement component C5a induces the expression of oncostain M via AP-1 activation.   Arterioscler Thromb Vasc Biol 2008 Vol. 3 p498-503.

6.883

6.    

Geiger M.   Soluble protein C receptor: why?.   Blood 2008 Vol. 111, No. 7, p3301-3302.

10.896

7.    

Nonas S, Birukova AA, Fu P, Xing J, Chatchavalvanich S, Bochkov VN, Leitinger N, Garcia JG, Birukov KG.   Oxidized phospholipids reduce ventilator-induced vascular leak and inflammation in vivo.   Crit Care 2008, Vol 12 No.1, R27 p1-13.

3.116

8.    

Schabbauer G, Luyendyk J, Crozat K, Jiang Z, Mackman N, Bahram S, Georgel P.   TLR4/CD14-mediated P13K activation is an essential component of interferon-dependent VSV resistance in macrophages.   Molec Immunol 2008, Vol. 45, p2790-2796.

4.768

9.    

Rüger BM, Breuss J, Hollemann D, Yanagida G, Fischer MB, Mosberger I, Chott A, Lang I, Davis PF, Hoecker P, Dettke M.   Vascular morphogenesis by adult bone marrow progenitor cells in three-dimensional fibrin matrices.   Differentiation 2008, Vol. 76, p772-783.

3.745

10.    

Schmid JA, Birbach A.   IkappaB kinase beta (IKKb/IKK2/IKBKB) - A key molecule in signaling to the transcription factor NF-kappaB.   Cytokine Growth Factor Rev 2008, Vol. 19, p157-165.

11.549

11.    

Korkhov VM, Milan-Lobo L, Zuber B, Farhan H, Schmid JA, Freissmuth M, Sitte H.   Peptide-based interactions with Calnexin target misassembled membrane proteins into endoplasmic reticulum-derived multilamellar bodies.   J Mol Biol 2008, Vol. 378, p337-352.

4.890

12.    

Wiesner C, Winsauer G, Resch U, Hoeth M, Schmid JA, van Hengel J, van Roy F, Binder BR, de Martin R.   Alpha-Catulin, a Rho signaling component, can regulate NK-kappaB through binding to IKK-beta, and confers resistance to apoptosis.   Oncogene 2008, Vol. 27, p2159-2169.

6.582

13.  

Salzer U, Zhu R, Luten M, Isobe H, Pastushenko V, Perkmann T, Hinterdorfer P, and Bosman GJCGM.   Vesicles generated during storage of red cells are rich in the lipid raft marker stomatin.   Transfusion 2008, Vol. 48, p451-462.

3.374

14.    

Resch A, Afonyushkin T, Lombo TB, McDowall KJ, Blaesi U, Kaberdin VR.   Translational activation by the noncoding RNA DsrA involves alternative RNase III processing in the rpoS 5´leader.   RNA 2008, Vol. 14, No. 3, p454-459.

5.840

15.    

Philippova M, Ivanov D, Joshi MB, Kyriakakis E, Rupp K, Afonyushkin T, Bochkov V, Erne P, Resink TJ.   Identification of proteins associating with GPI-anchored T-cadherin on the surface of vascular endothelial cells: the role for Grp78/BiP in T-cadherin-dependent cell survival.   Mol Cell Biol 2008, Vol. 28, No. 12, p4004-4017.

6.773

16.    

Binder BR, Mihaly J.   The plasminogen activator inhibitor ?paradox? in cancer.   Immunol Lett. 2008, Vol. 16, No. 2, p116-124.

2.628

17.    

Kidd L, Schabbauer GA, Luyendyk JP, Holscher TD, Tilley RE, Tencati M, Mackman N.   Insulin Activation of the PI3K/Akt Pathway Reduces LPS-induced Inflammation in Mice.   J Pharmacol Exp Ther. 2008, Vol. 326, No. 1, p348-353.

4.003

18.    

Oskolkova OV, Afonyushkin T, Leitner A, von Schlieffen E, Gargalovic PS, Lusis AJ, Binder BR, Bochkov VN.   ATF4-dependent transcription is a key mechanism in VEGF upregulation by oxidized phospholipids: critical role of oxidized sn-2 residues in activation of unfolded protein response.   Blood 2008, Vol. 112, p330-339.

10.896

19.    

Jyrkkänen HK, Kansanen E, Inkala M, Kivelä AM, Hurttila H, Heinonen SE, Goldsteins G, Jauhiainen S, Tiainen S, Makkonen H, Oskolkova O, Alfonyushkin T, Koistinaho J, Yamamoto M, Bochkov VN, Ylä-Herttuala S, Levonen AL.   Nrf2 regulates antioxidant gene expression evoked by oxidized phospholipids in endothelial cells and murine arteries in vivo.   Circ Res. 2008, Vol. 103, p e1-e9.

9.721

20.    

Mille M, Koenig X, Zebedin E, Uhrin P, Cervenka R, Todt H, Hilber K.   Sodium current properties of primary skeletal myocytes and cardiomyocytes derived from different mouse strains.   Pfluegers Arch ? Eur J Physiol. 2008, DOI10.1007/s00424-008-0570-x

3.842

21.    

Resch U, Schichl YM, Sattler S, de Martin R.   XIAP regulates intracellular ROS by enhancing antioxidant gene expression.   Biochem Biophys Res Comm. 2008, Vol. 375, p 156-161.

2.479

22.    

Winsauer G, Resch U, Hofer Warbinek R, Schichl YM, de Martin R.   XIAP regulates bi-phasic NF-kappaB induction involving physical interaction and ubiquitination.   Cell Signal. 2008, Vol. 20, p 2107-2112.

4.147

23.    

Guenzl P, Schabbauer G.   Recent advances in the genetic analysis of PTEN and PI3K innate immune properties.   Immunobiology 2008, Vol. 213, p 759-765.

2.886

24.    

Hochrainer K, Kroismayr R, Baranyi U, Binder BR, Lipp J.   Highly homologous HERC proteins localize to endosomes and exhibit specific interactions with hPLIC and Nm23B.   Cell Molec Life Sci. 2008, Vol. 65, p 2105-2117.

5.239

25.    

Blueml S, Rosc B, Lorincz A, Seyerl M, Kirchberger S, Oskolkova O, Bochkov VN, Majdic O, Ligeti E, Stoeckl J.   The oxidation state of Phospholipids controls the oxidative burst in neutrophil granulocytes.   J of Immunol. 2008, Vol. 181, p 4347-4353.

6.239

26.    

Douglas YL, Mahtab EA, Jongbloed MR, Uhrin P, Zaujec J, Binder BR, Schalij MJ, Poelmann RE, Deruiter MC, Groot AC.   Pulmonary vein, dorsal atrial wall and atrial septum abnormalities in podoplanin Knockout mice with disturbed posterior heart field contribution .   Pediatr Res. 2008, [Epub ahead of print].

2.839

27.    

Sirotkin AV, Chrenek P, Rafay J, Omelka R, Vetr H, Jurcik R, Binder BR.   Some Endokrine Traits of Transgenic Rabbits. I. Changes in Plasma and Milk Hormones.   Physiol Res 2008, Vol. 57, p 735-743.

0.000

28.    

Prager GW, Mihaly J, Brunner PM, Koschelnick Y, Hoyer-Hansen G and Binder BR.   Urokinase (uPA) mediates endothelial cell survival via induction of the X-linked inhibitor of apoptosis protein (XIAP).   Blood 2008, [Epub ahead of print]

10.896

29.    

Hohensinner PJ, Kaun C, Rychli K, Niessner A, Pfaffenberger S, Rega G, Fuernkranz A, Uhrin P, Zaujec J, Afonyushkin T, Bochkov VN, Maurer G, Huber K, Wojta J.   The inflammatory mediator oncostain M induces stromal derived factor-1 in human adult cardiac cells.   FASEB J. 2008, Journal Article fj.08-108035 Published online November 19 2008.

6.791

30.    

Schiller HB, Szekeres A, Binder BR, Stockinger H, Leksa V.   M6P/IGF2R Limits cell invasion by controlling alphaVbeta3 Integrin expression and proteolytic processing of uPAR.   Mol Biol Cell. 2008, [Epub ahead of print] November 26 2008.

6.028